Luveris

Luveris® is the first and only pure recombinant human luteinizing hormone (r-hLH) available in the US. It is used in combination with GONAL-f® (follitropin alfa for injection) to stimulate follicular development in infertile hypogonadotropic hypogonadal (HH) women with profound LH deficiency (LH<1.2 IU/L). A definitive effect on pregnancy in this population has not been demonstrated. The safety and effectiveness of concomitant administration of Luveris with any other preparation of recombinant human FSH or urinary FSH is unknown.HH is a rare endocrine deficiency. Women with HH are unable to produce the hormones needed for full development of follicles in the ovaries, ovulation and growth of the lining of the uterus sufficient to support implantation of a fertilized egg and early pregnancy. Luveris® addresses an unmet medical need and has received Orphan Drug exclusivity from the FDA.

Luveris is sold as individual vials. Each vial contains 75 IU powder and solvent for solution for injection. The vial and the solvent need to be mixed together, it does not come in premixed syringes.

Luveris on IVFPharmacy is made by Serono Pharmaceuticals. It is a brand medication, not generic. The drug composition is exactly the same as Luveris in the US but the packaging may vary slightly.

 

Luveris, an LH hormone injection, is used alongside other hormone drugs FSH and hCG to help women suffering from infertility to conceive. The combination of LH and FSH hormones encourages healthy egg development ovulation of mature eggs. Luveris is only effective in women who’s ovaries still produce eggs. The medication should not be used in women who have ovarian failure or who are post menopause.

Common Luveris side effects include: Redness/pain at the injection site, headache, tiredness, or mild nausea.

Serious Luveris side effects that need medical attention include: Weakness on one side of the body, slurred speech, vision changes, sudden/severe headache, pain/swelling of the calf muscles, chest pain, shortness of breath, swelling of ankles/hands/feet or signs of OHSS (ovarian hyperstimulation syndrome)

Disclaimer: information taken from webMD.com